Release date: 2008-09-01
Recently, British scientists have discovered a protein in immune cells that may become a reliable marker of the risk of schizophrenia.
About 1% of people are said to be plagued by schizophrenia. The current diagnosis of this disease relies on the subjective judgment of clinical face-to-face and the assessment of unclear symptoms, which often leads to delays in diagnosis and treatment. Therefore, biomarkers may be an effective diagnostic tool for indicating the risk and onset of schizophrenia.
The researchers identified two peaks that showed significant changes by comparing the protein profiles of patients with schizophrenia and normal subjects. Both proteins have been identified as alpha-defensins, a protein used to kill microbes and viruses in an innate immune response.
By detecting the level of alpha-defensin in the blood, scientists found that all alpha-defensin levels in patients with confirmed schizophrenia were significantly elevated. This change was also found in some newly diagnosed patients, indicating that high levels of alpha-defensins are not caused by the development of drugs or diseases.
Researchers believe that they can be used as an effective and simple marker for assessing the risk of schizophrenia. However, the development of a sensitive, specific schizophrenia blood test method requires more markers.
Source: Meditech Medical Network
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