The Brigham Gynecology Hospital affiliated with Harvard University in the United States conducted a “Doctor Health Studyâ€. Since 1997, 14 641 male doctors over the age of 50 have been observed, 5% of whom were suffering from heart disease.
The researchers divided the doctors into four groups, taking vitamin E and vitamin C regularly, taking vitamin E and vitamin C, or taking a placebo that did not contain the active ingredients of the two vitamins. Among them, the dose of vitamin E is 400 international units every other day, and vitamin C is 500 mg per day.
The results showed that after 8 years, there was no difference in the proportion of patients with myocardial infarction, stroke or death from heart-related diseases. However, 39 doctors taking vitamin E suffered from a hemorrhagic stroke, compared with 23 in the other population, indicating that those taking vitamin E were 74% more likely to have the disease than others.
Another study by the University of Oxford in the United Kingdom found that vitamin B12 and vitamin B9 did not prevent heart disease. The study looked at more than 12,000 people who had had a history of myocardial infarction.
The results of the above research were published online in the Journal of the American Medical Association.
Palbociclib is a drug for the treatment of ER-positive and HER2-negative breast cancer developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
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