Pharmacological effects
Antibacterial and antiviral effects:
Fructus Arctii aqueous extract (1:2) in the test tube for Trifolium frondosa, concentric hairy algae, Xanthorhabdum globifolia, sphagnum sphaeroides, wool-like spores, inguinal epidermis Nine strains of pathogenic fungi such as bacteria, red epidermophytes, Nocardia star, and Rust spores have antibacterial activity. There are data indicating that the extract of Arctium lappa has anti-HIV (HIv) activity.
[hypoglycemic effect]:
Burdock extract can significantly reduce blood glucose in rats for a long time and increase the tolerance to carbohydrates. Normal mice contain 0.25% calf
Diet or its decoction substitute for drinking water for 28 days, the results did not affect the glucose balance parameters in mice, while streptozotocin diabetic mice, burdock can prevent diabetes symptoms.
Calcium antagonism:
Guinea pig colon tape test proved. Calcium aglycone has obvious calcium antagonistic effect. Inhibition of high potassium-induced contraction, PA2 value of 6.60 for the commonly used calcium antagonist verapamil 1/6, spontaneously hypertensive rats intravenously 10mg/kg has a significant and long-lasting antihypertensive effect.
[Role of kidney disease]:
Intraperitoneal injection of aminonucleosides causes nephropathy in rats. Intraperitoneal injection of arfactorin can inhibit the increase of urinary protein excretion and improve serum biochemical indicators, suggesting anti-nephropathy. Abdomino injection of bovine glycoside has almost no effect on the increase of protein excretion, but oral administration is effective. It is presumed that it may be hydrolyzed into aborigin in the digestive tract to produce anti-nephropathy.
Anti-tumor and anti-mutagenic effects:
An antimutagenic factor was isolated from burdock. The relative molecular mass exceeds 300,000. Heat-resistant, resistant to protease, sensitive to manganese chloride treatment.
[Other effects]:
Arctiin has an expansion effect on the frog's lower extremities and rabbit ear blood vessels, transiently lowering blood pressure, and has inhibitory or paralytic effects on isolated rabbit uterine, intestinal, motor, and osseous muscles. Mild diuretic, purgative effect.
toxic side effect
5. Arctiin can cause tonic convulsions in frogs, mice, and rabbits. Breathing is weak, free movement disappears, and finally it turns into paralysis. At this time, the heart has not stopped beating.
Adverse reactions
Wu Shuzhong reported 1 case of allergic reactions caused by burdock fruit.
We're Professional Supplier Extract Powder manufacturers and suppliers in China specialized in providing high-quality products at low price. We warmly welcome you to buy or wholesale bulk Supplier Extract Powder for sale here from our factory. For a free sample, contact us now.
Supplier Extract Powder,Supplier Extract ,Supplier Powder Manufacturer in China
Shaanxi Kang New Pharmaceutical co., Ltd. , https://www.kangnewpharma.com